How should pilocarpine be stored?

• A. At room temperature or refrigerated if it is a gel
• B. Frozen
• C. Exposed to light
• D. In a humid environment

Answer: (A)

Storage stability for pilocarpine depends on the formulation. Most pilocarpine ophthalmic products are stable at room temperature, which is why storing it there is appropriate. If the product is a gel, refrigeration can be acceptable or even preferred to maintain the gel’s texture and potency, so keeping it in the fridge is allowed for that form.

Freezing can disrupt the formulation, potentially causing precipitation or changes in texture and potency. Exposing the drug to light can promote degradation for some formulations, and storing in a humid environment can increase contamination risk. Following the label directions is best, but in general, room temperature is suitable, with refrigeration reserved for specific gel formulations.