In drug discovery terminology, what are hits?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $24.99Unlock all

Prepare for the Drug Action 2 Exam. Focus on multiple-choice questions, learn through interactive quizzes, and understand core drug mechanisms with explanations. Dive deep into pharmacokinetics and pharmacodynamics to ace your test!

Multiple Choice

In drug discovery terminology, what are hits?

Explanation:
Hits are newly identified compounds that show measurable activity in an screening assay against the target. They are active, meaning they produce the desired biological effect, but they are not yet developed or optimized. From a large library, these hits serve as starting points to confirm activity, establish dose–response, and assess specificity, with the goal of turning the most promising ones into leads that can be optimized for potency, selectivity, and drug-like properties. This distinguishes them from already approved drugs, known inactive compounds, or candidates that have already been refined during lead optimization.

Hits are newly identified compounds that show measurable activity in an screening assay against the target. They are active, meaning they produce the desired biological effect, but they are not yet developed or optimized. From a large library, these hits serve as starting points to confirm activity, establish dose–response, and assess specificity, with the goal of turning the most promising ones into leads that can be optimized for potency, selectivity, and drug-like properties. This distinguishes them from already approved drugs, known inactive compounds, or candidates that have already been refined during lead optimization.

More Multiple Choice Questions
Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy